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Standard Mesothelioma Treatments
Important considerations in determining a mesothelioma treatment plan include the cancer stage, primary site affected and cell type. Treatment options also depend on whether the cancer is localized to the chest or has spread to the chest wall, diaphragm, or lymph nodes as well as your age and overall health. The three standard therapies used to treat mesothelioma include surgery, chemotherapy, and radiation.
In many cases, mesothelioma specialists will recommend a multimodal approach, which uses a combination of these three types of treatment. In various studies, multimodal treatment has been shown to be more effective than any of these individual treatments alone. For example, surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) has resulted in an increase in the life expectancy of peritoneal mesothelioma patients in recent years.
Multimodal treatment typically consists of a primary treatment used in combination with a neoadjuvant therapy (a “helper” treatment before the primary treatment) or an adjuvant treatment (a helper treatment after the primary treatment). For example, one multimodal approach might include:
- Neoadjuvant therapy: Radiation to shrink the tumor size
- Primary treatment: Surgery to remove the tumor
- Adjuvant therapy: Chemotherapy to kill any remaining cells
The treatment plan will be developed in conjunction with a mesothelioma specialist who can provide details about the specific therapy approach being taken.
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